Wednesday, July 1, 2009
Diprivan, Generic Name: Propofol (PROE-poe-fol)
What is Diprivan?
Diprivan is used to start or maintain anesthesia during certain surgeries, tests, or procedures. It may also be used for other conditions as determined by your doctor.
Diprivan is a general anesthetic. It is unknown exactly how this medication works.
Do NOT use this medication if:
· you are allergic to any ingredient in this medication
· you are allergic to eggs, egg products, soybeans, or soy products
Contact your doctor or health care provider right away if any of these apply to you.
Before using Diprivan :
Some medical conditions may interact with this medication . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
· if you are pregnant, planning to become pregnant, or are breast-feeding
· if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
· if you have allergies to medicines, foods, or other substances
· if you have inflammation of the pancreas, high lipid levels in the blood, or epilepsy
Some MEDICINES MAY INTERACT with this medication . Tell your health care provider if you are taking any other medicines, especially any of the following:
· Benzodiazepines (eg, alprazolam), narcotic pain relievers (eg, morphine), or other sedatives (eg, chloral hydrate) because they may increase the risk of this medication 's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if this medication may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Diprivan is used to start or maintain anesthesia during certain surgeries, tests, or procedures. It may also be used for other conditions as determined by your doctor.
Diprivan is a general anesthetic. It is unknown exactly how this medication works.
Do NOT use this medication if:
· you are allergic to any ingredient in this medication
· you are allergic to eggs, egg products, soybeans, or soy products
Contact your doctor or health care provider right away if any of these apply to you.
Before using Diprivan :
Some medical conditions may interact with this medication . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
· if you are pregnant, planning to become pregnant, or are breast-feeding
· if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
· if you have allergies to medicines, foods, or other substances
· if you have inflammation of the pancreas, high lipid levels in the blood, or epilepsy
Some MEDICINES MAY INTERACT with this medication . Tell your health care provider if you are taking any other medicines, especially any of the following:
· Benzodiazepines (eg, alprazolam), narcotic pain relievers (eg, morphine), or other sedatives (eg, chloral hydrate) because they may increase the risk of this medication 's side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if this medication may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Diprivan (Propofol)
Propofol is a short-acting intravenous nonbarbiturate sedative agent used for the induction of general anesthesia for adults and children, maintenance of general anesthesia, and sedation in medical contexts, such as intensive care unit (ICU) sedation for intubated, mechanically ventilated adults, and in procedures such as colonoscopy and endoscopy, as well as in dental surgery. Its widespread use as an anesthetic induction agent has largely replaced that of Sodium Pentothal. Although propofol is not considered an analgesic drug, one study has found a lower incidence of postoperative pain after propofol anesthesia compared to anesthesia with inhalation agents. Propofol is approved for use in more than 50 countries. It is also commonly used in veterinary medicine.
Abuse
Abuse of propofol as a recreational drug has been reported, usually among medical staff such as anaesthetists who have access to the drug. Despite a lack of analgesic properties, propofol's sedative action presumably produces euphoric effects. The steep dose response curve of the drug makes such abuse very dangerous without proper monitoring, and several deaths have been recorded.
Notable individuals
Well-known people who have been involved in hazardous use or harmful use of Propofol, or who have exhibited dependence on the drug, include:
· Michael Jackson, pop singer. It is confirmed that Jackson went into cardiac arrest on June 25, 2009. Propofol was found in his home .
Abuse
Abuse of propofol as a recreational drug has been reported, usually among medical staff such as anaesthetists who have access to the drug. Despite a lack of analgesic properties, propofol's sedative action presumably produces euphoric effects. The steep dose response curve of the drug makes such abuse very dangerous without proper monitoring, and several deaths have been recorded.
Notable individuals
Well-known people who have been involved in hazardous use or harmful use of Propofol, or who have exhibited dependence on the drug, include:
· Michael Jackson, pop singer. It is confirmed that Jackson went into cardiac arrest on June 25, 2009. Propofol was found in his home .
Jackson asked for powerful sedative(Diprivan (propofol), nurse says
More questions about Michael Jackson’s medications arose Tuesday when a nurse came forward to say that Jackson had asked her in April for a power sedative.
Cherilyn Lee, a registered nurse who operates a Los Angeles-based nutritional counseling business, told CNN that Jackson was complaining of insomnia and pleaded for her to get him some Diprivan (propofol), a drug usually used to start or maintain anesthesia during surgeries.
Lee said she told Jackson “the medication is not safe.”
Four days before Jackson’s death, Lee said, a Jackson staffer called and said the pop star was complaining that one side of his body was hot and the other side was cold .
“You need to go to hospital,” she told the staffer, with Jackson apparently in earshot.
An injection of Diprivan can induce hypnosis within 40 seconds from the start of injection, according to the U.S. Food and Drug Administration.
The drug’s product label says that propofol should only be administered by people “trained in the administration of general anesthesia.” Sedated patients should be continuously monitored, the product label says, and equipment to provide artificial ventilation, administration of oxygen and instituting CPR “must be immediately available.”
The product label warns that use of propofol for sedating adult and pediatric intensive care unit patients has been associated with organ system failures that have resulted in death.
Cherilyn Lee, a registered nurse who operates a Los Angeles-based nutritional counseling business, told CNN that Jackson was complaining of insomnia and pleaded for her to get him some Diprivan (propofol), a drug usually used to start or maintain anesthesia during surgeries.
Lee said she told Jackson “the medication is not safe.”
Four days before Jackson’s death, Lee said, a Jackson staffer called and said the pop star was complaining that one side of his body was hot and the other side was cold .
“You need to go to hospital,” she told the staffer, with Jackson apparently in earshot.
An injection of Diprivan can induce hypnosis within 40 seconds from the start of injection, according to the U.S. Food and Drug Administration.
The drug’s product label says that propofol should only be administered by people “trained in the administration of general anesthesia.” Sedated patients should be continuously monitored, the product label says, and equipment to provide artificial ventilation, administration of oxygen and instituting CPR “must be immediately available.”
The product label warns that use of propofol for sedating adult and pediatric intensive care unit patients has been associated with organ system failures that have resulted in death.
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