Diprivan (Propofol)

Propofol is a short-acting intravenous nonbarbiturate sedative agent used for the induction of general anesthesia for adults and children, maintenance of general anesthesia, and sedation in medical contexts, such as intensive care unit (ICU) sedation for intubated, mechanically ventilated adults, and in procedures such as colonoscopy and endoscopy, as well as in dental surgery. Its widespread use as an anesthetic induction agent has largely replaced that of Sodium Pentothal. Although propofol is not considered an analgesic drug, one study has found a lower incidence of postoperative pain after propofol anesthesia compared to anesthesia with inhalation agents. Propofol is approved for use in more than 50 countries. It is also commonly used in veterinary medicine.

Abuse

Abuse of propofol as a recreational drug has been reported, usually among medical staff such as anaesthetists who have access to the drug. Despite a lack of analgesic properties, propofol's sedative action presumably produces euphoric effects. The steep dose response curve of the drug makes such abuse very dangerous without proper monitoring, and several deaths have been recorded.

Notable individuals

Well-known people who have been involved in hazardous use or harmful use of Propofol, or who have exhibited dependence on the drug, include:

· Michael Jackson, pop singer. It is confirmed that Jackson went into cardiac arrest on June 25, 2009. Propofol was found in his home .